/NaiveTcell " \o "Naive T cell " napve responses , although B-cells and macrophages can be important APCs . Since antibody cannot enter infected cells and phagocytes cannot detect that they are infected , cytotoxic T-cells must be activated to recognize and kill the infected cells . To be activated by endogenous antigen , CD8 T-cells use their T-cell receptor TCR to bind endogenous antigen peptides presented on membrane Class I MHC proteins of target or infected cells . T-cell precursors however arrive to the thymus from the...











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