The importance of tight blood glucose control was demonstrated by the Diabetes Control and Complications Trial (DCCT , a 10-year prospective clinical trial conducted from 1983 to 1993 . The trial investigated the impact of intensive glucose control on the development and progression of complications such as retinopathy , nephropathy , and neuropathy . A cohort of 1 , 441 people with type 1 diabetes were randomly assigned to conventional treatment (one or two insulin injections per day ) or intensive treatment (three or four insulin injections...











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