Paper Topic:

effect of a strong selective agent (tetracycline) on bacterial community composition

Running Head : TETRACYCLINE AND BACTERIAL COMMUNITY COMPOSITION

Effect of Tetracycline on Staphylococcus and Escherichia Community Composition

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Abstract

The aim of the study was to investigate the effects on growth and composition of Staphylococcus and Escherichia in tetracycline seeded cultures . Separately prepared bacterial cultures were mixed to generate a mixed culture and incubated for two weeks under different tetracycline concentration and against a control for cross reference . Basically , a control aids as a determinant of the proportion of Staphylococcus growth

in the absence of the effect of tetracycline . The results indicated that as the concentration of tetracycline increased , so was a slight transient quantitative decrease to a significant quantitative decrease in the growth and composition of bacterial flora . These interferences with normal bacterial activity are not only in tandem with the avalanche of research findings on the effects of a strong selective agent on Staphylococcus community composition but also encouraging in reference to the therapeutic advantage of tetracycline based antibiotics

Introduction

Tetracycline belongs to a family of broad spectrum antibiotics that inhibit bacterial protein synthesis through the prevention of the binding of amino acyl to transfer ribonucleic acid to the ribosome Tetracycline exists in a wide variety of derivatives but only a few derivatives have a proven usefulness in clinical drug therapy . Apart from tetracycline itself , oxytetracycline , chlortetracycline , doxycline and minocycline are some of the derivatives in common use (Chopra Howe 1978

Apart from being an alternative therapeutic option in human beings tetracyclines constitute a...

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