Vicodin

Vicodin

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Abstract

Vicodin (hydrocodone and acetaminophen combination ) is one of the most prescribed pain medicines . The special combination of acetaminophen and hydrocodone makes Vicodin to be a powerful antipyretic , analgesic and antitussive medicine . The two compounds act in synergy in the management of cough symptoms , fever and pain (Chabdrasekharan , et al , 2002 . In the , individual pharmacokinetics of the two compounds that make up Vicodin will be discussed giving details the mode of action of both compounds . Indications of Vicodin will also be considered highlighting

when the drug is used and the possible side effects . There are dangers that result following concomitant Vicodin administration with other drugs . The will examine these dangers and provide co-morbidity and age limitations when using Vicodin . Monitoring discussion will credit the importance of physician monitoring in managing any side effects that may arise . The will conclude by stating the exact dosage recommended among patients in to avoid overdose

Introduction ?-epoxy-3-methoxy-17-methomorphinan-6-one tartrate is an antitussive and an opioid analgesic which occurs as fine crystalline or white crystalline powder . Acetaminophen , chemically 4 '-hydroxyaxetanilide (C8H9NO2 , is sparingly bitter , white in color crystalline powder . It is a non salicylate , non opiate and non steroidal anti-inflammatory drug (NSAID ) that elicits antipyretic and analgesic properties partly through the inhibition of cyclooxygenase (COX ) activity (Chandrasekharan et al 2002 . Cyclooxygenase enzymes are involved in prostaglandin production Vicodin contains other inactive compounds which include colloidal silicon dioxide , croscarmellose sodium , starch , dibasic calcium phosphate , microcrystalline cellulose , stearic acid and...