Nutrution

The Promise of Nutrigenomics in Diabetes Healthcare Management

The Centers for Disease Control and Prevention defines Diabetes (CDC ) as a disease in which blood glucose levels are above normal . Most of the food we eat is turned into glucose , or sugar , for our bodies to use for energy . The pancreas , an organ that lies near the stomach , makes a hormone called insulin to help glucose get into the cells of our bodies When you have diabetes , your body either doesn 't make enough insulin or can 't use its own insulin as well

as it should . This causes sugar to build up in your blood . Diabetes can cause serious health complications including heart disease , blindness , kidney failure , and lower-extremity amputations . The prevalence of the disease has a people , 6 .3 of the population have diabetes . The number of people diagnosed is 13 .0 million people , and the undiagnosed is 5 .2 million people . Diabetes is the sixth leading cause of death in the United States

Recent progress in the areas of molecular and recombinant DNA technology has led to sophisticated research in genetics . DNA sequencing has made us acknowledge the uniqueness of individuals that come with genetic variation . Nutrigenomics encompasses a wide array of technologies that deal with how genetic programs present in cells and tissues may possibly be affected by diet . The following are three possible definitions of nutrigenomics : 1 ) . the application of high throughput genomics tools in nutrition research 2 ) . seeks to examine `dietary signatures ' in cells , tissues and organisms and to understand how nutrition influences homeostasis and 3 ) . the interface between the nutritional environment and cellular / genetic processes

All of these definitions have commonalities with other omics disciplines , specifically pharmacogenomics and pharmacogenetics . However stark differences are noted for instance , nutrigenomics presents complications that the other two areas do not , particularly the length and the complexity of exposures . Research along this area has progressed in the past two decades , with physicians , geneticists , and nutritionists showing interest to the influences of genetic variation and gene-nutrient interactions in the management of diseases including coronary heart disease , hypertension , cancer , diabetes and obesity Moreover , these have also investigated the roles of nutrients in gene expression . These have successfully paved the way for the discipline of nutrigenetics and nutrigenomics

The current seeks to investigate the influence of this new and promising discipline to the management of diabetes . These researches seek to demonstrate the benefits of this new science to the treatment of this debilitating disease . Wareham (in Burton Stewart , 2004 ) asserts that most researches have held that diabetes and obesity are conditions that diet gene interaction does not influence . He depicted these as commendable areas for study , and reinforced that even in such common conditions , there will still be considerable research issues and challenges (Wareham in Burton Stewart , 2004 . He then suggested that the investigation of the relationship between genetic variation and diet in the management of diabetes be carefully tackled to avoid public confusion in the awareness campaigns...