`Endocrine Disruptors`.

Endocrine Disruptors

Introduction

The normal physiological functions of the body are regulated in a complex process which involves signaling process from an organ to a target tissue or organ . The signals are hormones released from organs like pituitary gland , adrenal , thymus , pancreas , testes and ovaries which are secreted directly in to the blood stream , the signals are then conveyed to the target organs depending on stage of life for example growth , reproduction , development and maturation . Once these signals reach the target organ they bind to a receptor after which they trigger

br the required responses for instance regulation of body sugar or concentration of salt in body fluids . The effect of these messengers is either an increase or reduction in the target substance which is determined by either a change in environment or a need of a certain substance when its time during growth finds use in the body

Endocrine Disruptors

Sometimes analogues or substances similar in structure to some of the endocrine hormones

bind to the receptors preventing the binding of the substance supposed to bind on that receptor resulting in ill health . This limits the normal physiological functions of the body . Disruption by these analogues may be by interfering with the normal hormonal balance , changing the passage routes of the hormones or by stopping hormone stimulation . Most of the disruptors are chemical substances found in products like pesticides insecticides , fungicides and other agricultural and industrial chemicals which lead to occupational toxicology or poisoning . These chemicals can also passed through...