The Differences of Prader Willi Syndrome (PWS) and Angelman Syndrome (AS) and ways to help these children.

The following compilation is a of Prader-Willi Syndrome and Angelman Syndrome , two neurodevelopmental conditions , which will be examined , and through questioning , the search for evidence for a possible distinction between the two diss . Samples of case studies , evolving around the inquiry of the ratio of male v . female diagnosis , will assist in creating a summary , and final report in the quest for the solution of how children affected by these two syndromes can be assisted with daily functions , such as education , will temporarily close this document but persist in being a corner

stone in the continued research of Prader-Willi Syndrome and Angelman Syndrome

What is Prader-Willi Syndrome and Angelman Syndrome

Though the two diss share symptoms , and distinguishable physical features , and are considered diss resulting from the same affected chromosome region , 15q11-q13 , according to the research results found at the Department of Pediatrics , Okayama University Graduate School of Medicine and Dentistry , based in Okayama , Japan PWS (Prader-Willi Syndrome ) results from the loss of expression of paternally expressed genes and AS (Angelman Syndrome ) of maternally based genes (Ninomiya Yokoyama , Kawakami , Une , Maruyama Morishima , 541

Are there shared symptoms between PWS and AS

According to research outcomes cataloged at the Department of Pediatrics , National Taiwan University Hospital in Taiwan , Phenotypes typically include severe to profound psychomotor retardation , abnormal EEG , infantile spasm /epilepsy , hypotonia , behavioral problems , and only mild dysmorphic features a number of features common to PW or AS were .such as .small hands and feet .hyperextensible joints seizure , language impairment , and strabismus (Hou Wang , 126

Case study examples of paternal /maternal inheritance

The following information is a compilation of research findings cataloged in the February 2005 issue of the Journal of Autism and Developmental Diss , based upon clinical studies conducted in UK and companioned by results achieved through the department of pediatrics at the Okayama University Graduate School of Medicine and Dentistry based in Okayama , Japan their clinical studies were addressed in Pediatrics International (2005

The research conducted and compiled in UK directly focuses upon paternal inheritance of PWS /AS , in which the patient (a five year old female the parents , two siblings , and a paternal uncle were also tested for similar traits , to show genetic link to the patient of focus . Some of the characteristics examined were intellectual level , early speech and language development , and motor skill development , individually , along with cataloging physical features present with the patient in comparison to her family members . Family history was taken into account with the following : There is a family history of manic-depressive in a maternal grandparent and a psychiatric illness , which at stages has been attributed to depression or dementia in a paternal grandparent . In a maternal aunt there is a history of learning difficulties (Veltman Thompson , Craig , Dennis , Roberts , Moore , Brown Bolton , 119

The conclusion of the study conducted with the family was found that the mother didn 't possess the duplicated gene , although she generated a history of developmental delays and learning difficulties in the academic setting , according to...